Regenerative Surgery responds to the fundamental ethical principle "primum non nocere" by offering patients effective therapies with minimum risk. Regenerative Surgery intervenes on the suffering organs and tissues by stimulating their natural capacity for self-repair and functional recovery. The bio-medical approach of Regenerative Surgery is based on the use of stem cells, biochemical mediators and tissue engineering. The Unit of Surgery and Regenerative Medicine, MSW (Regenerative Surgery Unit) of Villa Aurora, is a new model of health care that integrates clinical, scientific and research activities. The RSU is composed of a multidisciplinary team that involves the surgeon, the biologist, the laboratory technician, the radiologist, the physiotherapist and the medical director; an alliance that guarantees the effectiveness of care and patient safety. As part of clinical activities, treatments are provided to improve the symptoms of osteoarticular diseases through tissue regeneration. Scientific activity and research deal with communication, training, refresher courses, data collection and scientific publications.