1. PRP (Platelet-rich plasma)
PRP is a platelet concentrate obtained by centrifuging the patient's blood. The PRP contains several growth factors such as PDGF; VEGF; TGF-b1; EGF; FGF-ß; IGF-1. Research has shown that in vitro PRP has anti-inflammatory and trophic properties, stimulating the regeneration of connective tissues. In clinical practice, the current limit of PRP lies in the fact that it is a fluid preparation which rapidly spreads into the recipient tissue, stimulating it only fleetingly. This high diffusibility reduces its regenerative effectiveness. The anti-inflammatory and trophic properties of PRP are used for the treatment of initial symptomatic osteoarthritis, tendinopathies, fasciitis and bursitis. PRP is also used in plastic and cosmetic surgery and, more recently, in general surgery.